Polycystic ovary syndrome:Prevalence and phenotypic characteristics in Women in Kano, northern Nigeria
Abstract
Abstract Page
Polycystic ovary syndrome: prevalence and phenotypic characteristics in women in a named geographic location.
Abstract:
Context:
Polycystic ovary syndrome (PCOS) is a common reproductive and endocrine disorder that is found in 6 -10% women, presenting with menstrual abnormalities, hyper-androgenism and polycystic ovaries. One of the complications of PCOS is metabolic syndrome.
Based on the Rotterdam criteria for diagnosis, 3 phenotypes of PCOS exist: the Classical, hyperandrogenic-anovulatory, ovulatory and the normoandrogenic types, each with different cardiometabolic risk profile.
There is paucity of studies on the prevalence of PCOS in this locality and the different phenotypes in the country.
Aim:
The aim of this study was to determine the prevalence and phenotypic characteristics of PCOS in Women of reproductive age in the state.
Settings and Design:
A cross sectional study was conducted on 597 women (18-45years) that attended the Gynecologic clinics at 2 institutions during the period.
Methods and Material:
Patients with Anovulation and clinical hyperandrogenism were recruited consecutively. Their clinical, anthropometric, biochemical and ultrasound indices were obtained.
Statistical analysis used:
Data was analyzed with MINITAB express for MAC. Measured variables were expressed in descriptive statistics. Tests of association for qualitative variables were performed using the chi-square test.
Results:
Polycystic ovary syndrome had a prevalence of 6.2%. Classical type was present in 67.6%, while the normo-ovulatory type was present in 2.7%. About 70% were overweight. Abnormal waist circumference was found in 48.6% of the clients.
Conclusions:
PCOS had a prevalence of 6.2%, with classical type being the most common. Abnormal waist circumference, a marker of metabolic risk was present in almost half of the cases.
Key-words: PCOS, Phenotypes, Cardio- metabolic risk.
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