The Hepatic Metastasis From Recurrent Ovarian Granulosa Cell Tumour: A Rare Entity

Abstract

Granulosa cell tumour (GCT) is a rare sex cord-stromal tumour of the ovary with considerable propensity for late recurrences. However, liver metastasis is extremely rare, with an incidence of 5-6%. We present a case report of remote recurrence of GCT with liver metastasis in a patient with a past surgical history for right ovarian GCT many years back. GCT primarily has a low malignant potential, but it has a high tendency to recur with metastasis, usually within the pelvis. Inhibin B and AMH are the most accurate tumour markers for the detection of recurrent GCT. Ultrasound of the abdomen revealed a complex solid cystic mass in the retroperitoneum and multiple hepatic lesions, the biopsy from which revealed metastatic GCT. Henceforth, the radiologists and gynaecologists need to be aware of delayed and remote recurrence of ovarian GCT with distant metastasis for prompt and appropriate management.